- Etymology
of Togaviridae based on Latin “cloak,” referencing the virus’ envelope.
- Togaviridae
and Flaviviridae split due to differences in molecular biology
- Two
Genera: Alphavirus and Rubivirus, separated via differences in
transmission
- Teratogen:
Congenital Rubella Syndrome associated with autism in children who’s
mother was infected
- Vaccine
is available for Rubella as a part of the trivalent MMR, made of live,
attenuated virus strain.
- One of
the Red Rashes of childhood, Rubella was a common viral exanthema in young
children before the creation of the vaccine.
- Toga
Alphaviruses comprise group A of Arboviruses: arthropod borne viral
diseases.
- Encephalitis
is caused by infection of the “roller coaster” alphaviruses: WEE, VEE,
EEE, EVE
- Febrile,
polyarthritic disease associated with infection of the other alphaviruses
(see intro page for list)
- Eradication: Rubella is effectively eradicated in the
US
due to vaccination. Meanwhile, non
human reservoirs prevent the eradication of many alphavirsues.